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Cat. No. | Product Name | Target | Signaling Pathways |
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T80057 |
Cytochrome P450 reductase
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Cytochrome P450reductase,一种NADPH-细胞色素还原酶,发挥作用于促进芳香酶构象,以最适合底物结合。 |
Cat. No. | Product Name | Species | Expression System |
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TMPH-01748 |
CYPOR Protein, Human, Recombinant (GST)
NADPH--cytochrome P450 reduct... |
Human | E. coli |
This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5. CYPOR Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 102.9 kDa and the accession number is P16435. | |||
TMPH-02801 |
CYPOR Protein, Mouse, Recombinant (His)
CYPOR,P450R,CPR,NADPH--cytochrome... |
Mouse | E. coli |
CYPOR Protein, Mouse, Recombinant (His) is expressed in E. coli. | |||
TMPH-00160 |
Cytochrome P450 BM-3 Protein, Bacillus megaterium, Recombinant (His & Myc)
cyp102A1,Bifunctional cytochrome P450/... |
Bacillus megaterium | E. coli |
Cytochrome P450 BM-3 Protein, Bacillus megaterium, Recombinant (His & Myc) is expressed in E. coli. | |||
TMPH-02618 |
CYP2E1 Protein, Mouse, Recombinant (His)
Cyp2e1,Cytochrome P450 2E1,Cytochrome<... |
Mouse | E. coli |
A cytochrome P450 monooxygenase involved in the metabolism of fatty acids. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Hydroxylates fatty acids specifically at the omega-1 position displaying the highest catalytic activity for saturated fatty acids. May be invo... | |||
TMPH-02140 |
CYP21A2 Protein, Human, Recombinant (E. coli, His)
Cytochrome P-450c21,Cytochrome P450 |
Human | E. coli |
A cytochrome P450 monooxygenase that plays a major role in adrenal steroidogenesis. Catalyzes the hydroxylation at C-21 of progesterone and 17alpha-hydroxyprogesterone to respectively form 11-deoxycorticosterone and 11-deoxycortisol, intermediate metabolites in the biosynthetic pathway of mineralocorticoids and glucocorticoids. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via... | |||
TMPH-02141 |
CYP21A2 Protein, Human, Recombinant (His)
Cytochrome P450 21,CYP21A2,Cytochrome<... |
Human | P. pastoris (Yeast) |
A cytochrome P450 monooxygenase that plays a major role in adrenal steroidogenesis. Catalyzes the hydroxylation at C-21 of progesterone and 17alpha-hydroxyprogesterone to respectively form 11-deoxycorticosterone and 11-deoxycortisol, intermediate metabolites in the biosynthetic pathway of mineralocorticoids and glucocorticoids. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via... | |||
TMPH-02139 |
CYP17A1 Protein, Human, Recombinant (GST)
Cytochrome P450 17A1,CYPXVII,CYP17A1,CYP17... |
Human | E. coli |
A cytochrome P450 monooxygenase involved in corticoid and androgen biosynthesis. Catalyzes 17-alpha hydroxylation of C21 steroids, which is common for both pathways. A second oxidative step, required only for androgen synthesis, involves an acyl-carbon cleavage. The 17-alpha hydroxy intermediates, as part of adrenal glucocorticoids biosynthesis pathway, are precursors of cortisol (Probable). Hydroxylates steroid hormones, pregnenolone and progesterone to form 17-alpha hydroxy metabolites, follow... |