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抑制剂 & 化合物

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重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T80057 Cytochrome P450 reductase

Cytochrome P450reductase,一种NADPH-细胞色素还原酶,发挥作用于促进芳香酶构象,以最适合底物结合。

化合物

Cytochrome P450 reductase
Cat.No: T80057
Synonym:
Target:
Cat. No. Product Name Species Expression System
TMPH-01748 CYPOR Protein, Human, Recombinant (GST)

NADPH--cytochrome P450 reduct...

Human E. coli
This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5. CYPOR Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 102.9 kDa and the accession number is P16435.
TMPH-02801 CYPOR Protein, Mouse, Recombinant (His)

CYPOR,P450R,CPR,NADPH--cytochrome...

Mouse E. coli
CYPOR Protein, Mouse, Recombinant (His) is expressed in E. coli.
TMPH-00160 Cytochrome P450 BM-3 Protein, Bacillus megaterium, Recombinant (His & Myc)

cyp102A1,Bifunctional cytochrome P450/...

Bacillus megaterium E. coli
Cytochrome P450 BM-3 Protein, Bacillus megaterium, Recombinant (His & Myc) is expressed in E. coli.
TMPH-02618 CYP2E1 Protein, Mouse, Recombinant (His)

Cyp2e1,Cytochrome P450 2E1,Cytochrome<...

Mouse E. coli
A cytochrome P450 monooxygenase involved in the metabolism of fatty acids. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Hydroxylates fatty acids specifically at the omega-1 position displaying the highest catalytic activity for saturated fatty acids. May be invo...
TMPH-02140 CYP21A2 Protein, Human, Recombinant (E. coli, His)

Cytochrome P-450c21,Cytochrome P450

Human E. coli
A cytochrome P450 monooxygenase that plays a major role in adrenal steroidogenesis. Catalyzes the hydroxylation at C-21 of progesterone and 17alpha-hydroxyprogesterone to respectively form 11-deoxycorticosterone and 11-deoxycortisol, intermediate metabolites in the biosynthetic pathway of mineralocorticoids and glucocorticoids. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via...
TMPH-02141 CYP21A2 Protein, Human, Recombinant (His)

Cytochrome P450 21,CYP21A2,Cytochrome<...

Human P. pastoris (Yeast)
A cytochrome P450 monooxygenase that plays a major role in adrenal steroidogenesis. Catalyzes the hydroxylation at C-21 of progesterone and 17alpha-hydroxyprogesterone to respectively form 11-deoxycorticosterone and 11-deoxycortisol, intermediate metabolites in the biosynthetic pathway of mineralocorticoids and glucocorticoids. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via...
TMPH-02139 CYP17A1 Protein, Human, Recombinant (GST)

Cytochrome P450 17A1,CYPXVII,CYP17A1,CYP17...

Human E. coli
A cytochrome P450 monooxygenase involved in corticoid and androgen biosynthesis. Catalyzes 17-alpha hydroxylation of C21 steroids, which is common for both pathways. A second oxidative step, required only for androgen synthesis, involves an acyl-carbon cleavage. The 17-alpha hydroxy intermediates, as part of adrenal glucocorticoids biosynthesis pathway, are precursors of cortisol (Probable). Hydroxylates steroid hormones, pregnenolone and progesterone to form 17-alpha hydroxy metabolites, follow...

重组蛋白

CYPOR Protein, Human, Recombinant (GST)
Cat.No: TMPH-01748
Species: Human
Expression System: E. coli
CYPOR Protein, Mouse, Recombinant (His)
Cat.No: TMPH-02801
Species: Mouse
Expression System: E. coli
Cytochrome P450 BM-3 Protein, Bacillus megaterium, Recombinant (His & Myc)
Cat.No: TMPH-00160
Species: Bacillus megaterium
Expression System: E. coli
CYP2E1 Protein, Mouse, Recombinant (His)
Cat.No: TMPH-02618
Species: Mouse
Expression System: E. coli
CYP21A2 Protein, Human, Recombinant (E. coli, His)
Cat.No: TMPH-02140
Species: Human
Expression System: E. coli
CYP21A2 Protein, Human, Recombinant (His)
Cat.No: TMPH-02141
Species: Human
Expression System: P. pastoris (Yeast)
CYP17A1 Protein, Human, Recombinant (GST)
Cat.No: TMPH-02139
Species: Human
Expression System: E. coli
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